Relationship of Intracellular Calcium and Oxygen Radicals to Cisplatin-Related Renal Cell Injury
Abstract.: We investigated the involvement of reactive oxygen species (ROS) and intracellular calcium in nephrotoxicity related to an antitumor agent, cisplatin. In this study, we employed cultured renal epithelial cells (LLC-PK1). Cisplatin at 500 µM significantly increased the production of ROS 5...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2006-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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