lncRNA SNHG1 induced by SP1 regulates bone remodeling and angiogenesis via sponging miR-181c-5p and modulating SFRP1/Wnt signaling pathway

• Main Authors: Xiao Yu (Author), Peng-Ze Rong (Author), Meng-Sheng Song (Author), Ze-Wen Shi (Author), Gong Feng (Author), Xian-Jun Chen (Author), Lin Shi (Author), Cheng-Hao Wang (Author), Qing-Jiang Pang (Author)
• Format: Book
• Published: BMC, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We aimed to investigate the functions and underlying mechanism of lncRNA SNHG1 in bone differentiation and angiogenesis in the development of osteoporosis. Methods The differential gene or proteins expressions were measured by qPCR or western blot assays, respectively. The target...