Autoantibody Profile of a Cohort of 54 Italian Patients with Linear IgA Bullous Dermatosis: LAD-1 Denoted as a Major Auto-antigen of the Lamina Lucida Subtype

• Main Authors: Emanuele Cozzani (Author), Giovanni di Zenzo (Author), Giulia Gasparini (Author), Adele Salemme (Author), Arianna Fay Agnoletti (Author), Camilla Vassallo (Author), Marzia Caproni (Author), Emiliano Antiga (Author), Angelo V. Marzano (Author), Riccardo Cavalli (Author), Corrado Ocella (Author), Clara De Simone (Author), Aurora Parodi (Author)
• Format: Book
• Published: Medical Journals Sweden, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Linear IgA bullous dermatosis (LABD) is characterized by presence of multiple IgA autoantibodies, and a comparatively lesser number of IgG antibodies, directed against different hemidesmosomal antigens. The main autoantigens are LAD-1, LABD-97, BP180 and BP230, type VII collagen and laminin 332. We...