Podocyte VEGF-A Knockdown Induces Diffuse Glomerulosclerosis in Diabetic and in eNOS Knockout Mice

• 主要な著者: Delma Veron (著者), Pardeep K. Aggarwal (著者), Qi Li (著者), Gilbert Moeckel (著者), Michael Kashgarian (著者), Alda Tufro (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Vascular endothelial growth factor-a (VEGF-A) and nitric oxide (NO) are essential for glomerular filtration barrier homeostasis, and are dysregulated in diabetic kidney disease (DKD). While NO availability is consistently low in diabetes, both high and low VEGF-A have been reported in patients with...