In vitro activity of levonadifloxacin, the active drug of orally administered prodrug alalevonadifloxacin against bloodstream isolates of Burkholderia pseudomallei

• Main Authors: Yamuna Devi Bakthavatchalam (Author), Yuvasri Manokaran (Author), Dhanalakshmi Venkatesan (Author), Karthik Gunasekaran (Author), Abi Manesh (Author), Barney Isaac (Author), Binesh Lal (Author), John Jude Antony Prakash (Author), Kamini Walia (Author), Balaji Veeraraghavan (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objective: Eradication of Burkholderia pseudomallei infections requires prolonged antibiotic treatment indicating microbiological and pharmacokinetic limitations of current options. Methods and results: Levonadifloxacin, a novel benzoquinolizine-fluoroquinolone available intravenously...