INGAP-Peptide Variants as a Novel Therapy for Type 1 Diabetes: Effect on Human Islet Insulin Secretion and Gene Expression

• Main Authors: James M. Porter (Author), Léa Guerassimoff (Author), Francisco Rafael Castiello (Author), André Charette (Author), Maryam Tabrizian (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2022-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Islet transplantation offers a long-term cure for Type 1 Diabetes (T1D), freeing patients from daily insulin injections. Therapeutic peptides have shown potential to increase the insulin output of pancreatic islets, maximizing the impact of grafted cells. The islet neogenesis-associated protein (ING...