Complexes of Ibuprofen Thiazolidin-4-One Derivatives with β-Cyclodextrin: Characterization and In Vivo Release Profile and Biological Evaluation

• 主要な著者: Ioana Mirela Vasincu (著者), Maria Apotrosoaei (著者), Florentina Lupascu (著者), Andreea-Teodora Iacob (著者), Simona-Eliza Giusca (著者), Irina-Draga Caruntu (著者), Narcisa-Laura Marangoci (著者), Anca Roxana Petrovici (著者), Gabriela Dumitrita Stanciu (著者), Bogdan-Ionel Tamba (著者), Bianca-Stefania Profire (著者), Alin-Viorel Focsa (著者), Mariana Pinteala (著者), Lenuta Profire (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2023-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Generally, NSAIDs are weakly soluble in water and contain both hydrophilic and hydrophobic groups. One of the most widely used NSAIDs is ibuprofen, which has a poor solubility and high permeability profile. By creating dynamic, non-covalent, water-soluble inclusion complexes, cyclodextrins (CDs) can...