Lineage analysis of circulating Trypanosoma cruzi parasites and their association with clinical forms of Chagas disease in Bolivia.

• Main Authors: Ramona del Puerto (Author), Juan Eiki Nishizawa (Author), Mihoko Kikuchi (Author), Naomi Iihoshi (Author), Yelin Roca (Author), Cinthia Avilas (Author), Alberto Gianella (Author), Javier Lora (Author), Freddy Udalrico Gutierrez Velarde (Author), Luis Alberto Renjel (Author), Sachio Miura (Author), Hiroo Higo (Author), Norihiro Komiya (Author), Koji Maemura (Author), Kenji Hirayama (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: The causative agent of Chagas disease, Trypanosoma cruzi, is divided into 6 Discrete Typing Units (DTU): Tc I, IIa, IIb, IIc, IId and IIe. In order to assess the relative pathogenicities of different DTUs, blood samples from three different clinical groups of chronic Chagas disease patie...