"Omics" and "epi-omics" underlying the β-cell adaptation to insulin resistance
Background: Pancreatic β-cells adapt to high metabolic demand by expanding their β-cell mass and/or enhancing insulin secretion to maintain glucose homeostasis. Type 2 diabetes (T2D) is typically characterized by β-cell decompensation. Scope of the review: The current review focuses on summarizing t...
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Format: | Llibre |
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Elsevier,
2019-09-01T00:00:00Z.
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