Cellular Ca2+ Dynamics in Urinary Bladder Smooth Muscle From Transgenic Mice Overexpressing Na+-Ca2+ Exchanger

• Main Authors: Hidemichi Murata (Author), Shingo Hotta (Author), Eiji Sawada (Author), Hisao Yamamura (Author), Susumu Ohya (Author), Satomi Kita (Author), Takahiro Iwamoto (Author), Yuji Imaizumi (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rise of Ca2+ concentration ([Ca2+] i ) by reducing external Na+ in urinary bladder smooth muscle cells (UBSMCs) from transgenic mice overexpressing Na+/Ca2+ exchanger type-1.3 (NCX1.3tg/tg) was about 4 times as large as that in the wild-type (WT). NCX1 protein expression in UB increased about 4-...