Design, synthesis, and evaluation of the novel ozagrel-paeonol codrug with antiplatelet aggregation activities as a potent anti-stroke therapeutic agent

• Main Authors: Chijing Zuo (Author), Fulong Yan (Author), Jie Wang (Author), Yulong Zhu (Author), Wenhui Luo (Author), Yan Liu (Author), Wanhui Liang (Author), Weidong Yu (Author), Jingwei Zhang (Author), Daiyin Peng (Author), Xiaodong Ma (Author), Can Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Ischemic stroke is the second most common chronic disease worldwide and is associated with high morbidity and mortality. Thromboembolism and platelet aggregation are the most characteristic features of stroke. Other than aspirin, no standard, accepted, or effective treatment for acute...