Design, synthesis, and evaluation of the novel ozagrel-paeonol codrug with antiplatelet aggregation activities as a potent anti-stroke therapeutic agent

• Үндсэн зохиолчид: Chijing Zuo (Зохиогч), Fulong Yan (Зохиогч), Jie Wang (Зохиогч), Yulong Zhu (Зохиогч), Wenhui Luo (Зохиогч), Yan Liu (Зохиогч), Wanhui Liang (Зохиогч), Weidong Yu (Зохиогч), Jingwei Zhang (Зохиогч), Daiyin Peng (Зохиогч), Xiaodong Ma (Зохиогч), Can Peng (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Introduction: Ischemic stroke is the second most common chronic disease worldwide and is associated with high morbidity and mortality. Thromboembolism and platelet aggregation are the most characteristic features of stroke. Other than aspirin, no standard, accepted, or effective treatment for acute...