LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma

• Main Authors: Yuantong Liu (Author), Shujin Li (Author), Shuo Wang (Author), Qichao Yang (Author), Zhizhong Wu (Author), Mengjie Zhang (Author), Lei Chen (Author), Zhijun Sun (Author)
• Format: Book
• Published: Nature Publishing Group, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cancer stem cell-like cells (CSCs) play an integral role in the heterogeneity, metastasis, and treatment resistance of head and neck squamous cell carcinoma (HNSCC) due to their high tumor initiation capacity and plasticity. Here, we identified a candidate gene named LIMP-2 as a novel thera...