Wenfei Buqi Tongluo Formula Against Bleomycin-Induced Pulmonary Fibrosis by Inhibiting TGF-β/Smad3 Pathway

• Main Authors: Lu Ding (Author), Yaxin Li (Author), Yingying Yang (Author), Siyu Song (Author), Hongyu Qi (Author), Jing Wang (Author), Ziyuan Wang (Author), Jiachao Zhao (Author), Wei Zhang (Author), Linhua Zhao (Author), Daqing Zhao (Author), Xiangyan Li (Author), Zeyu Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary fibrosis (PF) is the end stage of various chronic and progressive interstitial lung diseases. TGF-β, a profibrotic cytokine, can promote epithelial-mesenchymal transition (EMT), extracellular matrix (ECM) accumulation, and fibroblast proliferation, which contribute to progressive lung remo...