Aging-elevated inflammation promotes DNMT3A R878H-driven clonal hematopoiesis

• मुख्य लेखकों: Min Liao (लेखक), Ruiqing Chen (लेखक), Yang Yang (लेखक), Hanqing He (लेखक), Liqian Xu (लेखक), Yuxuan Jiang (लेखक), Zhenxing Guo (लेखक), Wei He (लेखक), Hong Jiang (लेखक), Jianwei Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2022-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Aging-elevated DNMT3A R882H-driven clonal hematopoiesis (CH) is a risk factor for myeloid malignancies remission and overall survival. Although some studies were conducted to investigate this phenomenon, the exact mechanism is still under debate. In this study, we observed that DNMT3A R878H bone mar...