The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains

• প্রধান লেখক: Eva Kudova (লেখক), Pavel Mares (লেখক), Martin Hill (লেখক), Katerina Vondrakova (লেখক), Grygoriy Tsenov (লেখক), Hana Chodounska (লেখক), Hana Kubova (লেখক), Karel Vales (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2021-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Pregnanolone glutamate (PA-G) is a neuroactive steroid that has been previously demonstrated to be a potent neuroprotective compound in several biological models in vivo. Our in vitro experiments identified PA-G as an inhibitor of <i>N</i>-methyl-<i>D</i>-aspartate receptors...