Marked irregular myofiber shape is a hallmark of human skeletal muscle ageing and is reversed by heavy resistance training

• Main Authors: Casper Soendenbroe (Author), Anders Karlsen (Author), Rene B. Svensson (Author), Michael Kjaer (Author), Jesper L. Andersen (Author), Abigail L. Mackey (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Age‐related loss of strength is disproportionally greater than the loss of mass, suggesting maladaptations in the neuro‐myo‐tendinous system. Myofibers are often misshaped in aged and diseased muscle, but systematic analyses of large sample sets are lacking. Our aim was to invest...