Pharmacokinetic improvement provided by microneedle patch in delivering bee venom, a case study in combating scopolamine-induced neurodegeneration in mouse model

• Main Authors: Cong Duc Nguyen (Author), Jaehee Yoo (Author), Eun Jin An (Author), Chang Yub Sung (Author), Do Hyeon Jeong (Author), Soo-Yeon Park (Author), Jae-Hong Kim (Author), Gihyun Lee (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Much research has shown Bee venom to be an effective neuroprotective agent. However, the usual transdermal injection of bee venom poses many pharmacokinetic disadvantages. Here, we compared the administration of bee venom via subcutaneous injection (SC) and via Microneedle patch (MN). Both administr...