New Nanoparticle Formulation for Cyclosporin A: In Vitro Assessment

• Main Authors: Amandine Gendron (Author), Natalie Lan Linh Tran (Author), Julie Laloy (Author), Romain Brusini (Author), Aurélie Rachet (Author), Frédéric Gobeaux (Author), Valérie Nicolas (Author), Pierre Chaminade (Author), Sonia Abreu (Author), Didier Desmaële (Author), Mariana Varna (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cyclosporin A (CsA) is a molecule with well-known immunosuppressive properties. As it also acts on the opening of mitochondrial permeability transition pore (mPTP), CsA has been evaluated for ischemic heart diseases (IHD). However, its distribution throughout the body and its physicochemical charact...