Performance of Cox proportional hazard models on recovering the ground truth of confounded exposure-response relationships for large‐molecule oncology drugs

Abstract A Cox proportional hazard (CoxPH) model is conventionally used to assess exposure-response (E-R), but its performance to uncover the ground truth when only one dose level of data is available has not been systematically evaluated. We established a simulation workflow to generate realistic E...

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Autores principales: Victor Poon (Autor), Dan Lu (Autor)
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Publicado: Wiley, 2022-11-01T00:00:00Z.
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Número de Clasificación: A1234.567
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