Omiganan Enhances Imiquimod‐Induced Inflammatory Responses in Skin of Healthy Volunteers

• প্রধান লেখক: Tessa Niemeyer‐van der Kolk (লেখক), Salma Assil (লেখক), Thomas P. Buters (লেখক), Melanie Rijsbergen (লেখক), Erica S. Klaassen (লেখক), Gary Feiss (লেখক), Edwin Florencia (লেখক), Errol P. Prens (লেখক), Jacobus Burggraaf (লেখক), Martijn B.A. vanDoorn (লেখক), Robert Rissmann (লেখক), Matthijs Moerland (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2020-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Omiganan (OMN; a synthetic cationic peptide) and imiquimod (IMQ; a TLR7 agonist) have synergistic effects on interferon responses in vitro. The objective of this study was to translate this to a human model for proof‐of‐concept, and to explore the potential of OMN add‐on treatment for viral skin dis...