3-Hydroxy-3-Methylglutaryl-COA Reductase Inhibitors and Phosphodiesterase Type V Inhibitors Attenuate Right Ventricular Pressure and Remodeling in a Rat Model of Pulmonary Hypertension

PURPOSE. We examined the inhibitory effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors and a phosphodiesterase type V inhibitor on hemodynamic function and cardiac remodeling in rats with monocrotaline-induced pulmonary hypertension. METHODS. The rat model of pulmonary hypertension...

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Main Authors: Mitsutoshi Satoh (Author), Akira Satoh (Author)
Format: Book
Published: Frontiers Media S.A., 2009-02-01T00:00:00Z.
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3rd Floor Main Library

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