Screening Repurposed Antiviral Small Molecules as Antimycobacterial Compounds by a Lux-Based phoP Promoter-Reporter Platform

• Main Authors: Li Zhu (Author), Annie Wing-Tung Lee (Author), Kelvin Ka-Lok Wu (Author), Peng Gao (Author), Kingsley King-Gee Tam (Author), Rahim Rajwani (Author), Galata Chala Chaburte (Author), Timothy Ting-Leung Ng (Author), Chloe Toi-Mei Chan (Author), Hiu Yin Lao (Author), Wing Cheong Yam (Author), Richard Yi-Tsun Kao (Author), Gilman Kit Hang Siu (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The emergence of multidrug-resistant strains and hyper-virulent strains of <i>Mycobacterium tuberculosis</i> are big therapeutic challenges for tuberculosis (TB) control. Repurposing bioactive small-molecule compounds has recently become a new therapeutic approach against TB. This study...