The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration

• Main Authors: Jinghui Xu (Author), Bin Zhang (Author), Jieyi Cai (Author), Qianqian Peng (Author), Junxia Hu (Author), Parizat Askar (Author), Jianghong Shangguan (Author), Wenfeng Su (Author), Changlai Zhu (Author), Hualin Sun (Author), Songlin Zhou (Author), Gang Chen (Author), Xiaoming Yang (Author), Yun Gu (Author)
• Format: Book
• Published: BMC, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Myelin sheath is a crucial accessory to the functional nerve-fiber unit, its disruption or loss can lead to axonal degeneration and subsequent neurodegenerative diseases (NDs). Notwithstanding of substantial progress in possible molecular mechanisms underlying myelination, there...