Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens

• المؤلفون الرئيسيون: Diego L. Costa (مؤلف), Eduardo P. Amaral (مؤلف), Bruno B. Andrade (مؤلف), Alan Sher (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2020-11-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Heme oxygenase-1 (HO-1) catalyzes the degradation of heme molecules releasing equimolar amounts of biliverdin, iron and carbon monoxide. Its expression is induced in response to stress signals such as reactive oxygen species and inflammatory mediators with antioxidant, anti-inflammatory and immunosu...