Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner

• Main Authors: Qian Zhao (Author), Yang Hu (Author), Shu Deng (Author), Pei Yu (Author), Bowen Chen (Author), Zuomin Wang (Author), Xiaozhe Han (Author)
• Format: Book
• Published: University of São Paulo, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Local administration of toll-like receptor 9 (TLR9), agonist cytidine-phosphate-guanosine oligodeoxynucleotide (CpG ODNs), and CD40 ligand (CD40L) can decrease ligature-induced periodontal inflammation and bone loss in wild type (WT) mouse. Objective: This study aimed to explore whether suc...