Effects of sphingosine and sphingosine analogues on the free radical production by stimulated neutrophils: ESR and chemiluminescence studies

• Main Authors: A. Mouithys-Mickalad (Author), G. Deby-Dupont (Author), M. Hoebeke (Author), M. Mathy-Hartert (Author), M. Lamy (Author), C. Deby (Author)
• 格式: 图书
• 出版: Hindawi Limited, 1997-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Sphingolipids inhibit the activation of the neutrophil (PMN) NADPH oxidase by protein kinase C pathway. By electron spin resonance spectroscopy (ESR) and chemiluminescence (CL), we studied the effects of sphingosine (SPN) and ceramide analogues on phorbol 12-myristate 13-acetate (PMA, 5 × 10-7M) sti...