5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice

• Main Authors: Moessner Rainald (Author), Gerlach Manfred (Author), Lesch Klaus-Peter (Author), Palm Florian (Author), Chen Yong (Author), Sommer Claudia (Author)
• Format: Book
• Published: SAGE Publishing, 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The role of serotonin (5-hydroxytrptamine, 5-HT) in the modulation of pain has been widely studied. Previous work led to the hypothesis that 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, might by itself influenc...