Founder mutations in Nepalese population

• Main Authors: Anurag Mehta (Author), Himanshi Diwan (Author), Garima Gupta (Author), Shrinidhi Nathany (Author), Shalini Agnihotri (Author), Surender Dhanda (Author)
• Formato: Libro
• Publicado: Korean Society of Pathologists & the Korean Society for Cytopathology, 2022-07-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Background Founder mutation is a heritable genetic alteration observed with high frequency in a geographically and culturally isolated population where one or more ancestors becomes the forebearer of the altered gene. The current study reports two founder mutations in the BRCA1 gene in the Nepalese...