Bulleyaconitine A Inhibits Morphine-Induced Withdrawal Symptoms, Conditioned Place Preference, and Locomotor Sensitization Via Microglial Dynorphin A Expression

• Váldodahkkit: Meng-Jing Zhao (Dahkki), Mi-Ya Wang (Dahkki), Le Ma (Dahkki), Khalil Ali Ahmad (Dahkki), Yong-Xiang Wang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Bulleyaconitine A (BAA), a C19-diterpenoid alkaloid, has been prescribed as a nonnarcotic analgesic to treat chronic pain over four decades in China. The present study investigated its inhibition in morphine-induced withdrawal symptoms, conditioned place preference (CPP) and locomotor sensitization,...