l‐Carnitine relieves cachexia‐related skeletal muscle fibrosis by inducing deltex E3 ubiquitin ligase 3L to negatively regulate the Runx2/COL1A1 axis

• Main Authors: Zongliang Lu (Author), Li Wang (Author), Zhenyu Huo (Author), Na Li (Author), Ning Tong (Author), Feifei Chong (Author), Jie Liu (Author), Yaowen Zhang (Author), Hongxia Xu (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer cachexia‐induced skeletal muscle fibrosis (SMF) impairs muscle regeneration, alters the muscle structure and function, reduces the efficacy of anticancer drugs, diminishes the patient's quality of life and shortens overall survival. RUNX family transcription factor 2...