Investigation on combined copy number variation sequencing and cytogenetic karyotyping for prenatal diagnosis

• Main Authors: Jinman Zhang (Author), Xinhua Tang (Author), Jilin Hu (Author), Guilin He (Author), Jian Wang (Author), Yingting Zhu (Author), Baosheng Zhu (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We aimed to evaluate the clinical value of copy number variation-sequencing (CNV-Seq) in combination with cytogenetic karyotyping in prenatal diagnosis. Methods CNV-Seq and cytogenetic karyotyping were performed in parallel for 9452 prenatal samples for comparison of the diagnost...