Regulatory T Cells: Potential Target in Anticancer Immunotherapy

• Main Authors: Chi-Mou Juang (Author), Chien-Fu Hung (Author), Jiun-Yih Yeh (Author), Huann-Cheng Horng (Author), Nae-Fong Twu (Author), Ming-Huei Cheng (Author), Kuo-Chang Wen (Author), Chiou-Chung Yuan (Author), Kuan-Chong Chao (Author), T-C Wu (Author), Ming-Shien Yen (Author)
• Format: Book
• Published: Elsevier, 2007-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The concept of regulatory T cells was first described in the early 1970s, and regulatory T cells were called suppressive T cells at that time. Studies that followed have demonstrated that these suppressive T cells negatively regulated tumor immunity and contributed to tumor growth in mice. Despite t...