Amniotic fluid-derived exosomes attenuated fibrotic changes in POI rats through modulation of the TGF-β/Smads signaling pathway

• Main Authors: Nahideh Nazdikbin Yamchi (Author), Shahin Ahmadian (Author), Halimeh Mobarak (Author), Farhad Amjadi (Author), Rahim Beheshti (Author), Amin Tamadon (Author), Reza Rahbarghazi (Author), Mahdi Mahdipour (Author)
• Format: Book
• Published: BMC, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract In the current study, we investigated the regenerative effects of amniotic fluid exosomes (AF-Exos) in a rat model for premature ovarian insufficiency (POI). POI is a condition characterized by a decrease in ovarian function that can lead to infertility. We induced POI by administering cycl...