Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

• Main Authors: Chun Jerold (Author), Aoki Junken (Author), Ma Lin (Author), Inoue Makoto (Author), Ueda Hiroshi (Author)
• Format: Book
• Published: SAGE Publishing, 2008-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Recently, we reported that lysophosphatidic acid (LPA) induces long-lasting mechanical allodynia and thermal hyperalgesia as well as demyelination and upregulation of pain-related proteins through one of its cognate receptors, LPA₁. In addi...