Speciation Analysis Highlights the Interactions of Auranofin with the Cytoskeleton Proteins of Lung Cancer Cells

• Main Authors: Monika Kupiec (Author), Agnieszka Tomaszewska (Author), Wioletta Jakubczak (Author), Maja Haczyk-Więcek (Author), Katarzyna Pawlak (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Two types of lung cells (epithelial cancer lung cells, A-549 and lung fibroblasts MRC-5) were exposed to the clinically established gold drug auranofin at concentrations close to the half-maximal inhibitory drug concentrations (IC₅₀). Collected cells were subjected to speciati...