Harmonizing solubility measurement to lower inter-laboratory variance - progress of consortium of biopharmaceutical tools (CoBiTo) in Japan

• প্রধান লেখক: Asami Ono (লেখক), Naoya Matsumura (লেখক), Takahiro Kimoto (লেখক), Yoshiyuki Akiyama (লেখক), Satoko Funaki (লেখক), Naomi Tamura (লেখক), Shun Hayashi (লেখক), Yukiko Kojima (লেখক), Masahiro Fushimi (লেখক), Hiroshi Sudaki (লেখক), Risa Aihara (লেখক), Yuka Haruna (লেখক), Maiko Jiko (লেখক), Masaru Iwasaki (লেখক), Takuya Fujita (লেখক), Kiyohiko Sugano (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: International Association of Physical Chemists (IAPC), 2019-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The purpose of the present study was to harmonize the protocol of equilibrium solubility measurements for poorly water-soluble drugs to lower inter-laboratory variance. The "mandatory" and "recommended" procedures for the shake-flask method were harmonized based on the knowledge...