LC-MS-based metabolomics in profiling of drug metabolism and bioactivation
Since metabolism significantly affects drug safety and efficacy, determining the metabolic profile of a drug is a critical part of drug development. The application of an LC-MS-based metabolomic approach has gained more widespread use in identifying drug metabolites, developing metabolic maps and le...
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Format: | Book |
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Elsevier,
2012-04-01T00:00:00Z.
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