LC-MS-based metabolomics in profiling of drug metabolism and bioactivation

Since metabolism significantly affects drug safety and efficacy, determining the metabolic profile of a drug is a critical part of drug development. The application of an LC-MS-based metabolomic approach has gained more widespread use in identifying drug metabolites, developing metabolic maps and le...

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Bibliographic Details
Main Authors: Feng Li (Author), Frank J. Gonzalez (Author), Xiaochao Ma (Author)
Format: Book
Published: Elsevier, 2012-04-01T00:00:00Z.
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