Nicotine-Induced Neurogenic Relaxation in the Mouse Colon: Changes With Dextran Sodium Sulfate-Induced Colitis

• Main Authors: Ikuo Murakami (Author), Yuri Hamada (Author), Satoshi Yamane (Author), Hiromichi Fujino (Author), Shunji Horie (Author), Toshihiko Murayama (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nicotine has been shown to reduce both tone and muscular activity in the human colon by releasing nitric oxide (NO) from nerves. To our knowledge, however, the effect of nicotine on mouse colon has not been elucidated, and the response in tissue from ulcerative colitis (UC) has not been investigated...