3D organoids derived from the small intestine: An emerging tool for drug transport research

• Main Authors: Yuanjin Zhang (Author), Shengbo Huang (Author), Weiguo Zhong (Author), Wenxia Chen (Author), Bingyi Yao (Author), Xin Wang (Author)
• 格式: 圖書
• 出版: Elsevier, 2021-07-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Small intestine in vitro models play a crucial role in drug transport research. Although conventional 2D cell culture models, such as Caco-2 monolayer, possess many advantages, they should be interpreted with caution because they have relatively poor physiologically reproducible phenotypes and funct...