3D organoids derived from the small intestine: An emerging tool for drug transport research

• Autori principali: Yuanjin Zhang (Autore), Shengbo Huang (Autore), Weiguo Zhong (Autore), Wenxia Chen (Autore), Bingyi Yao (Autore), Xin Wang (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Small intestine in vitro models play a crucial role in drug transport research. Although conventional 2D cell culture models, such as Caco-2 monolayer, possess many advantages, they should be interpreted with caution because they have relatively poor physiologically reproducible phenotypes and funct...