<i>Egr1</i> Gene Expression as a Potential Biomarker for In Vitro Prediction of Ocular Toxicity

• Main Authors: Da-Bin Hwang (Author), Shin-Young Kim (Author), Dong-Hoon Won (Author), Changuk Kim (Author), Yoo-Sub Shin (Author), Jong-Hwan Park (Author), Young-Jin Chun (Author), Kyung-Min Lim (Author), Jun-Won Yun (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Animal models are used for preclinical toxicity studies, and the need for in vitro alternative methods has been strongly raised. Our study aims to elucidate the potential mechanism of change in EGR1 expression under situations of toxic injury and to develop an <i>Egr1</i> promoter-lucife...