SERINC5 Is an Unconventional HIV Restriction Factor That Is Upregulated during Myeloid Cell Differentiation

• Автори: Ariane Zutz (Автор), Christian Schölz (Автор), Stephanie Schneider (Автор), Virginia Pierini (Автор), Maximilian Münchhoff (Автор), Kathrin Sutter (Автор), Georg Wittmann (Автор), Ulf Dittmer (Автор), Rika Draenert (Автор), Johannes R. Bogner (Автор), Oliver T. Fackler (Автор), Oliver T. Keppler (Автор)
• Формат: Книга
• Опубліковано: Karger Publishers, 2020-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Classical antiviral restriction factors promote cellular immunity by their ability to interfere with virus replication and induction of their expression by proinflammatory cytokines such as interferons. The serine incorporator proteins SERINC3 and SERINC5 potently reduce the infectivity of HIV-1 par...