Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model

Extensive loss of dopaminergic neurons and aggregation of the protein α-synuclein into ubiquitin-positive Lewy bodies represents a major neuropathological hallmark of Parkinson's disease (PD). At present, the generation of large nuclear-associated Lewy bodies from endogenous wild-type α-synucle...

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Bibliographic Details
Main Authors: Teresa R. Taylor-Whiteley (Author), Christine L. Le Maitre (Author), James A. Duce (Author), Caroline F. Dalton (Author), David P. Smith (Author)
Format: Book
Published: The Company of Biologists, 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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