Toward Mechanistic Design of Surrogate Buffers for Dissolution Testing of pH-Dependent Drug Delivery Systems

• Автори: Johannes Andreas Blechar (Автор), Jozef Al-Gousous (Автор), Christoph Wilhelmy (Автор), Annika Marielina Postina (Автор), Marcus Getto (Автор), Peter Langguth (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2020-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The in vivo dissolution of enteric-coated (EC) products is often overestimated by compendial in vitro dissolution experiments. It is of great interest to mimic the in vivo conditions as closely as possible in vitro in order to predict the in vivo behavior of EC dosage forms. The reason behind this i...