Cerebrospinal fluid concentrations of fluoroquinolones and carbapenems in tuberculosis meningitis

• Main Authors: Nicole F. Maranchick (Author), Mohammad H. Alshaer (Author), Alison G. C. Smith (Author), Teona Avaliani (Author), Mariam Gujabidze (Author), Tinatin Bakuradze (Author), Shorena Sabanadze (Author), Zaza Avaliani (Author), Maia Kipiani (Author), Charles A. Peloquin (Author), Russell R. Kempker (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Tuberculosis meningitis (TBM) is the most lethal form of TB. It is difficult to treat in part due to poor or uncertain drug penetration into the central nervous system (CNS). To help fill this knowledge gap, we evaluated the cerebrospinal fluid (CSF) concentrations of fluoroquinolones an...