Self-delivering prodrug-nanoassemblies fabricated by disulfide bond bridged oleate prodrug of docetaxel for breast cancer therapy

• Main Authors: Shenwu Zhang (Author), Jibin Guan (Author), Mengchi Sun (Author), Dong Zhang (Author), Haotian Zhang (Author), Bingjun Sun (Author), Weiling Guo (Author), Bin Lin (Author), Yongjun Wang (Author), Zhonggui He (Author), Cong Luo (Author), Jin Sun (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breast cancer leads to high mortality of women in the world. Docetaxel (DTX) has been widely applied as one of the first-line chemotherapeutic drugs for breast cancer therapy. However, the clinical outcome of DTX is far from satisfaction due to its poor drug delivery efficiency. Herein, a novel disu...