Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain

• Main Authors: Vadim Yakhnitsa (Author), Guangchen Ji (Author), Matthew Hein (Author), Peyton Presto (Author), Zack Griffin (Author), Olga Ponomareva (Author), Edita Navratilova (Author), Frank Porreca (Author), Volker Neugebauer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Functional pain syndromes (FPS) occur in the absence of identifiable tissue injury or noxious events and include conditions such as migraine, fibromyalgia, and others. Stressors are very common triggers of pain attacks in various FPS conditions. It has been recently demonstrated that kappa opioid re...