Vericiguat, a novel sGC stimulator: Mechanism of action, clinical, and translational science

• Asıl Yazarlar: Maria E. Trujillo (Yazar), Surya Ayalasomayajula (Yazar), Robert O. Blaustein (Yazar), Ferdous Gheyas (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Vericiguat, a novel soluble guanylate cyclase (sGC) stimulator, is approved for the treatment of heart failure (HF) with reduced ejection fraction (HFrEF). Decreased nitric oxide (NO) availability, sGC desensitization to NO, sGC deficiency, and reduced cyclic guanosine monophosphate (cGMP)...