Anticancer Dose Adjustment for Patients with Renal and Hepatic Dysfunction: From Scientific Evidence to Clinical Application

• Main Authors: Tomi Hendrayana (Author), André Wilmer (Author), Verena Kurth (Author), Ingo GH Schmidt-Wolf (Author), Ulrich Jaehde (Author)
• Format: Book
• Published: MDPI AG, 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most anticancer agents exhibit a narrow therapeutic index, i.e., a small change in plasma concentrations can lead to a less efficacious treatment or an unacceptable degree of toxicity. This study aimed at providing health professionals with a feasible and time-saving tool to adapt the dose of antica...