Characterization of global transcription profile of normal and HPV-immortalized keratinocytes and their response to TNF treatment

• Main Authors: Colo Anna (Author), Martins Waleska K (Author), Hirata Roberto (Author), Esteves Gustavo H (Author), Boccardo Enrique (Author), Termini Lara (Author), Neves E Jordão (Author), Villa Luisa (Author), Reis Luiz FL (Author)
• Format: Book
• Published: BMC, 2008-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Persistent infection by high risk HPV types (e.g. HPV-16, -18, -31, and -45) is the main risk factor for development of cervical intraepithelial neoplasia and cervical cancer. Tumor necrosis factor (TNF) is a key mediator of epitheli...