Selective cytotoxic activity and protective effects of sodium ascorbate against hepatocellular carcinoma through its effect on oxidative stress and apoptosis in vivo and in vitro

• Main Authors: Yousra M. El-Far (Author), Ahmed E. Khodir (Author), Ahmad O. Noor (Author), Deina M. Almasri (Author), Alaa A. Bagalagel (Author), Reem M. Diri (Author), Hussam I. Kutbi (Author), Mohammed M. H. Al-Gayyar (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Hepatocellular carcinoma (HCC) is characterized by elevated in oxidative stress and inflammatory cytokines, which enhance destructive effects of the tumor. Therefore, we conducted this study to investigate the protective effects of sodium ascorbate against thioacetamide-induced HCC in ra...